• Only of ICD implantations are performed

  2019-05-28

  

  Only 1% of ICD implantations are performed in children. As a result, established methods of pediatric ICD implantation are lacking, and long-term outcomes are still unclear. Non-transvenous ICD systems are required in children [1,2], and we chose an epicardial system for our case. The advantage of t

• br Conclusions br Disclosures br Funding Sources br

  2019-05-27

  

  Conclusions Disclosures Funding Sources Introduction Pulmonary vein isolation (PVI) has become an accepted treatment for atrial fibrillation (AF) [1]. The efficacy of PVI is sometimes insufficient, and atrial substrate modification of target specific AF signals indicating the substrate r

• br I Campo de maniobras

  2019-05-27

  

  I. Campo de maniobras II. Las letras III. La historia IV. Las humanidades VI. La Revolución mexicana VI. Últimos refuerzos VII. Conclusión Atrás han quedado la suplantación de la obra creativa, y de la crítica, por la insaciable teoría; las insostenibles muertes de la novela, de

• Subalternidad y contras Nuestra lectura est enmarcada por pr

  2019-05-27

  

  Subalternidad y “contras” Nuestra lectura está enmarcada por principios teóricos retomados de los Estudios Subalternos. Identificamos casein kinase 2 inhibitor los campesinos, especialmente a los participantes en las guerras civiles, como subalternos. Interpretamos que las formas en que se represen

• While it has been reported that the combination therapy

  2019-05-27

  

  While it has been reported that the combination therapy of As2O3 and ATRA is highly effective not only as the front-line treatment [6], but also in relapsed and treatment-refractory APL patients [7], showing fewer adverse events than the combination of ATRA and chemotherapeutic drugs, the efficacy a

• ALW-II-41-27 Combined use of two AADs

  2019-05-27

  

  Combined use of two AADs was more frequent in persistent (6.7%) and LS-persistent AF (7.5%) patients than in PAF patients (2.8%, pALW-II-41-27 prescribed at the time of discharge in the three AF types. The choice of bepridil was dependent on the type of AF (PAF 10.6% vs. non-PAF 30.3%, p Discussio

• br The L type calcium channel

  2019-05-27

  

  The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot

• The Zika virus epidemic is

  2019-05-24

  

  The Zika virus epidemic is spreading: 63 countries are now reporting transmission, over 1500 cases of related microcephaly or CNS malformations have been confirmed this year, and knowledge on the disease is advancing slowly. Adding to the tension around Zika, at the epicentre of the outbreak, Brazil

• In Telek Ayove and colleagues

  2019-05-24

  

  In , Telek Ayove and colleagues report a comparison of the Dual Path Platform (DPP) Syphilis Screen and Confirm test (Chembio Diagnostic Systems, Medford, NY, USA) with non-treponemal (RPR) and treponemal (TPHA) serological tests for diagnosis of yaws in two remote communities in Papua New Guinea wi

• Findings Between July and March we enrolled pregnant women t

  2019-05-24

  

  Findings Between July, 2013, and March, 2015, we enrolled 324 pregnant women (162 to each study group); 18 women were lost to follow up before delivery. Measurements of biomarkers made more than 60 days before randomisation (17 participants) or more than 300 days after randomisation (26 participants

• br In the past decade Brazil

  2019-05-24

  

  In the past decade, Brazil has achieved considerable progress in malaria control, with 140 000 cases reported in 2015, the lowest numbers since 1980. Part of this success has been attributed to the establishment of a large network of around 3000 diagnostic and treatment units for malaria. A remark

• Amiodarone has been used in Japan for more than years

  2019-05-24

  

  Amiodarone has been used in Japan for more than 5 years now since its approval in July 2007, and intravenous amiodarone has been widely used for life-threatening ventricular tachycardia in the setting of critical care medicine. However, only few reports have been published in the international liter

• CT analysis of tumour bearing bones showed significantly inc

  2019-05-24

  

  μCT analysis of tumour bearing bones showed significantly increased bone density in animals receiving zoledronic acid, alone or in combination with doxorubicin, compared to PBS control. Our results confirmed that a single dose of zoledronic ag1478 caused sustained bone effects throughout the experi

• In addition to inducing IKs dysfunction through dominant

  2019-05-24

  

  In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor

• NSC 687852 Moving forward we identify several urgent

  2019-05-24

  

  Moving forward, we identify several urgent needs and challenges. First, the standing of NSC 687852 health workers in the health-care systems needs to be legitimised and moved away from largely grant-funded temporary employees or volunteers who might provide educational services towards skilled memb

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