• The majority of breast malignancies are hormone responsive

  2019-06-20

  

  The majority of breast malignancies are hormone responsive, and adjuvant endocrine therapy is used routinely to prevent breast cancer recurrence and death [6,7]. Tamoxifen was the past treatment of choice for endocrine-responsive postmenopausal breast cancer and was found to preserve BMD in postmeno

• br Descripci n de las variantes Las variantes en los

  2019-06-20

  

  Descripción de las variantes Las variantes en los dos poemas estudiados a veces son leves: puntuación, acentuación o actualización de la ortografía. Pero cuando las acotaciones implican cambio de léxico o la sustitución de una parte o de un verso completo, constituyen un problema textual que ayud

• Performance based financing often highlighted in Rwanda s st

  2019-06-20

  

  Performance-based financing, often highlighted in Rwanda\'s story, has had mixed results when applied elsewhere, partly because of breakdowns in execution. For example, the failure of the performance-based financing initiative in neighbouring Uganda was caused by challenges in setting targets, deliv

• La pregunta que fundamenta esta investigaci n es

  2019-06-20

  

  La pregunta que fundamenta esta investigación es acerca de la posibilidad de que los participantes de experiencias de acción colectiva urbana definan y re-definan sus pertenencias Sulfaphenazole la región y las naciones en las que se insertan. Este acercamiento a las representaciones que los sujetos

• br Conflict of interest br Acknowledgments This research was

  2019-06-20

  

  Conflict of interest Acknowledgments This research was supported by the Grants from the National Natural Science Foundation of China (No. 31270820 and No. 81230061 to Wei-Dong Han, No. 81402567 to Ya-jing Zhang) and was partially supported by a Grant from the National Basic Science and Develop

• br Conflict of interest br Acknowledgments This research was

  2019-06-20

  

  Conflict of interest Acknowledgments This research was supported by the Grants from the National Natural Science Foundation of China (No. 31270820 and No. 81230061 to Wei-Dong Han, No. 81402567 to Ya-jing Zhang) and was partially supported by a Grant from the National Basic Science and Develop

• It is recommended that pilsicainide be administered

  2019-06-20

  

  It is recommended that pilsicainide be administered over 10min, with 1.0mg/kg being the maximum daily dosage allowed. However, a single oral dose of pilsicainide has been shown to be effective, feasible and safe, and the single dose is always from 100 to 150mg [4,10]. Both the time to maximum drug c

• The principal difference between BrS

  2019-06-20

  

  The principal difference between BrS and ERS is related to the region of the ventricle most affected. Epicardial mapping studies in BrS patients report accentuated J waves and fragmented and/or late potentials in the epicardial region of the RVOT [129–131], whereas in ERS only accentuated J waves,

• Vollmer and colleagues distinctive multilevel modelling has

  2019-06-20

  

  Vollmer and colleagues\' distinctive multilevel modelling has potential weaknesses that warrant further investigation. The authors imply that tremendous statistical power is derived from the availability of Demographic and Health Survey data for about 460 000 children and their households. But becau

• HIV counselling and testing is the essential

  2019-06-20

  

  HIV counselling and testing is the essential first step to accessing HIV care services and is also recognised as an HIV prevention strategy because knowledge of HIV status reduces risky sexual behaviours. A reduction in the number of sexual partners has been reported, but not a significant increase

• Al observar las cuatro constituciones Brasil Argentina

  2019-06-20

  

  Al observar las cuatro constituciones (Brasil, Argentina, Paraguay y Uruguay) se destaca una ejemplar redacción del Artículo 47 de la Constitución de Uruguay, al definir cuál es la prioridad en el uso del recurso además de determinar no sólo la participación social en la planificación de estrategias

• Recently emerging data suggest that lower frequency of IV

  2019-06-19

  

  Recently emerging data suggest that lower frequency of IV bisphosphonates in metastatic breast cancer has the same efficacy as monthly regimen [48]. ONJ on the other hand can be extremely symptomatic with a severely detrimental effect on quality of life. A case-control study based on risk factors f

• Extensive vascularization of the skeletal tissue suggests

  2019-06-19

  

  Extensive vascularization of the skeletal tissue suggests the importance of blood vessels in regulating its physiological functions. Endothelium, the innermost cellular layer of blood vessels forms a central component of the bone marrow vascular microenvironment [7]. Recent evidence support that a p

• In addition to inducing IKs dysfunction through dominant neg

  2019-06-19

  

  In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor

• In our study of patients we demonstrated the highly accurate

  2019-06-19

  

  In our study of 24 patients, we demonstrated the highly accurate identification of PVPs by using the HDMM. These findings aligned with several other studies applying high-density mapping catheters such as either the HDMM or other comparable basket catheters [9–11]. As confirmed by the study group of

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