• br Discussion Furthermore most of the previously described

  2019-06-26

  

  Discussion Furthermore most of the previously described cases with a solitary lesion affecting bone involved the craniofacial bones [2–7], and only a few cases affected the appendicular skeleton. Several affected extra-craniofacial sites have been sporadically reported, for example: femur [8], ti

• br Future perspectives Identification of LOX as a modulator

  2019-06-26

  

  Future perspectives Identification of LOX as a modulator of the ECM to form pre-metastatic niches and subsequently bone metastasis arose as we were investigating the hypoxia tumour secretome using existing patient cohort data and cutting edge proteomics. Although condoned by some researchers as “

• Introduction Dabigatran Boehringer Ingelheim Ingelheim Germa

  2019-06-26

  

  Introduction Dabigatran (Boehringer Ingelheim, Ingelheim, Germany) is a direct thrombin inhibitor, which can be orally administered, and is used to decrease the risk of ischemic stroke in patients with non-valvular atrial fibrillation (NVAF). In early phase studies of dabigatran in healthy men, his

• br Discussion The present meta

  2019-06-26

  

  Discussion The present meta-analysis of randomized trials demonstrated that treatment with AAMs is associated with an increase in non-cardiac and all-cause mortality as compared to non-arrhythmic therapy or control group. There was no significant reduction in cardiac or arrhythmic mortality betwe

• Cerrone et al reported that the mechanism of

  2019-06-26

  

  Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje

• A comienzos del siglo xx

  2019-06-26

  

  A comienzos del siglo xx, en el imaginario criollista y en un sentido similar al que intentamos planear aquí en lo que Sulbactam las disidencias sexuales respecta, el personaje inmigrante permanecía siempre en un segundo plano respecto del héroe, siempre criollo. Al inmigrante italiano, así como les

• To our knowledge this is

  2019-06-25

  

  To our knowledge, this is the first survey to specifically assess, in daily clinical practice, the management of bone U-104 and, in general, the perception of bone healthcare in Italy. However, the findings of this analysis are in overall agreement with those of previous studies, some referring to

• br Conclusion br Conflicts of

  2019-06-25

  

  Conclusion Conflicts of interest Acknowledgments Case report A 56-year-old woman with prior history of dual-chamber permanent pacemaker (PPM) implantation (ELA Medical Symphony DR 2550, ELA Medical, Montrouge, France) for symptomatic complete Tranilast block presented to the Cardiac Rhyt

• We propose that the same geospatial statistical techniques c

  2019-06-25

  

  We propose that the same geospatial statistical techniques can be applied to HIV. We used these techniques to estimate the number of HIV-infected individuals in Maseru (a health-care district in Lesotho) and establish their geographical location. The district of Maseru is a relatively large area, ab

• In Richard Walker and colleagues report the results of a

  2019-06-25

  

  In , Richard Walker and colleagues report the results of a case-control study of risk factors for stroke in Tanzania. Their study makes several important contributions. First, they provide the first information about importance of risk factors for stroke in urban and rural Tanzania, and confirm the

• Babies and children feature heavily in this August issue

  2019-06-25

  

  Babies and children feature heavily in this August issue of , as well they should at a time when unfinished agendas are top of the agenda. In its 2014 report on the , released on July 7, the UN described the under-5 mortality goal as “slipping away from achievement by 2015”. The research and opinion

• br After several decades of community based interventions an

  2019-06-25

  

  After several decades of community-based interventions and surveillance, on Nov 15, 2016, Morocco was recognised by WHO as having eliminated trachoma as a public health problem. A formal ceremony, involving the handover of a letter of recognition from Margaret Chan, WHO\'s Director-General, marked

• Importance of heart failure Acute decompensated heart failur

  2019-06-25

  

  Importance of Clofarabine failure Acute decompensated heart failure (ADHF) refers to a clinical condition of worsening HF with dyspnea, often with evidence of fluid overload [1]. This is generally triggered by 1 of the 4 main factors: atrial fibrillation, anemia, hypertension, and medication/dietar

• In this case report we described a rare

  2019-06-25

  

  In this case report, we described a rare case of tumor lysis syndrome associated with the FOLFOX regimen and further stress the importance of additional prophylaxis for the huge tumor burden. Our patient\'s hyperammonemia may be due to cardiogenic shock, post cardio-pulmonary-cerebral resuscitation

• br Statistical power and analysis

  2019-06-25

  

  Statistical power and analysis A description of the statistical analysis of the study has been published previously [23]. For the analysis of the results at the 5-year time point, comparisons were expressed graphically using 95% confidence intervals. Statistical analysis was performed using SPSS

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