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ALW-II-41-27 Combined use of two AADs
2019-05-27

Combined use of two AADs was more frequent in persistent (6.7%) and LS-persistent AF (7.5%) patients than in PAF patients (2.8%, pALW-II-41-27 prescribed at the time of discharge in the three AF types. The choice of bepridil was dependent on the type of AF (PAF 10.6% vs. non-PAF 30.3%, p Discussio
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br The L type calcium channel
2019-05-27

The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot
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The Zika virus epidemic is
2019-05-24

The Zika virus epidemic is spreading: 63 countries are now reporting transmission, over 1500 cases of related microcephaly or CNS malformations have been confirmed this year, and knowledge on the disease is advancing slowly. Adding to the tension around Zika, at the epicentre of the outbreak, Brazil
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In Telek Ayove and colleagues
2019-05-24

In , Telek Ayove and colleagues report a comparison of the Dual Path Platform (DPP) Syphilis Screen and Confirm test (Chembio Diagnostic Systems, Medford, NY, USA) with non-treponemal (RPR) and treponemal (TPHA) serological tests for diagnosis of yaws in two remote communities in Papua New Guinea wi
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Findings Between July and March we enrolled pregnant women t
2019-05-24

Findings Between July, 2013, and March, 2015, we enrolled 324 pregnant women (162 to each study group); 18 women were lost to follow up before delivery. Measurements of biomarkers made more than 60 days before randomisation (17 participants) or more than 300 days after randomisation (26 participants
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br In the past decade Brazil
2019-05-24

In the past decade, Brazil has achieved considerable progress in malaria control, with 140 000 cases reported in 2015, the lowest numbers since 1980. Part of this success has been attributed to the establishment of a large network of around 3000 diagnostic and treatment units for malaria. A remark
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Amiodarone has been used in Japan for more than years
2019-05-24

Amiodarone has been used in Japan for more than 5 years now since its approval in July 2007, and intravenous amiodarone has been widely used for life-threatening ventricular tachycardia in the setting of critical care medicine. However, only few reports have been published in the international liter
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CT analysis of tumour bearing bones showed significantly inc
2019-05-24

μCT analysis of tumour bearing bones showed significantly increased bone density in animals receiving zoledronic acid, alone or in combination with doxorubicin, compared to PBS control. Our results confirmed that a single dose of zoledronic ag1478 caused sustained bone effects throughout the experi
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In addition to inducing IKs dysfunction through dominant
2019-05-24

In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor
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NSC 687852 Moving forward we identify several urgent
2019-05-24

Moving forward, we identify several urgent needs and challenges. First, the standing of NSC 687852 health workers in the health-care systems needs to be legitimised and moved away from largely grant-funded temporary employees or volunteers who might provide educational services towards skilled memb
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br En las p ginas de
2019-05-24

En las páginas de La esquina de los ojos rojos, jóvenes “pránganas” escapando MRS 2578 Supplier toda velocidad sobre una motoneta, una vez cometido un asesinato, huyen a toda costa de una realidad vengativa, de los límites de un vacío personal, ético y de las cerradas posibilidades de esa asfixia
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Con esto no se pretende se alar que en
2019-05-24

Con esto no se pretende señalar que en el terreno educativo no existan mentes lúcidas o que sus actores se comporten con una meridiana ingenuidad. Solamente queremos advertir que la constante necesidad de mejorar la educación y de aggiornar sus procesos 4-ap la dinámica cambiante de la sociedad, hac
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The patient was consented to treatment on clinical trial
2019-05-23

The patient was consented to treatment on clinical trial NCT02527447 and received treatment with salvage chemotherapy of mitoxantrone 12mg/m2/day IV on days 1–3, etoposide 200mg/m2/day continuous IV infusion (CIV) on days 8–10, and cytarabine 500mg/m2/day CIV on days 1–3 and 8–10 (EMA). Infectious p
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Programmed death ligand PD L expression is a characteristic
2019-05-23

Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed
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CT analysis of tumour bearing bones
2019-05-23

μCT analysis of tumour bearing bones showed significantly increased bone density in animals receiving zoledronic acid, alone or in combination with doxorubicin, compared to PBS control. Our results confirmed that a single dose of zoledronic SB203580 caused sustained bone effects throughout the expe
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