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br Introduction Cardiovascular diseases rank
2018-11-02
Introduction Cardiovascular diseases rank the first in cause of death, which account for ∼30% of all deaths worldwide (Mozaffarian et al., 2015). Unlike robust cardiac regeneration observed in adult zebrafish and embryonic and neonatal mice (Porrello et al., 2011; Poss et al., 2002; Sturzu et al.
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By conditional ablation of Dicer specifically in bona fide
2018-11-02
By conditional ablation of Dicer specifically in bona fide aNSCs of the adult hippocampus in vivo and in vitro and by manipulation of specific miRNAs, here we studied the role of miRNAs for lineage fate choice of aNSCs. Our study identified a set of 11 miRNAs that, by synergistic enforcement of gene
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In future experiments long term cultures of BBB models
2018-11-02
In future experiments, long-term cultures of BBB models could be of interest, offered potentially by the use of dynamic flow culture conditions, to further study chronic diseases such as Alzheimer\'s disease and Parkinson\'s disease. In this lysophosphatidic acid respect, there is increasing intere
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The growth or the attenuation of
2018-11-02
The growth or the attenuation of the external load increases the augend in Eq. (1) and transmits the ordered motion to twinning dislocations in the twinning plane and in the twinning direction. The interaction of a twin with stoppers in metals slows down its growth and contributes a component influ
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In principle any hexagon having
2018-11-02
In principle, any hexagon having two neighboring mutually antithetic pentagons is capable of embedding a dimer. However, it methysergide can embed a hexagon having not only two neighboring mutually antithetic pentagons, but one pentagon and a mutually antithetic square. Such a possibility appears
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There is a growing interest in
2018-11-02
There is a growing interest in the impact of stress including cumulative adversity over the lifetime, and the physiological toll resulting from ongoing activation of stress responses at or around the time of childbearing (Phelan et al., 2015; Hobel, Goldstein, and Barrett, 2008; Dominguez et al., 20
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br Materials and method br Results Fig shows the age
2018-11-02
Materials and method Results Fig. 1 shows the age-standardized annual probability of death among U.S-born women aged 45–89 years by U.S. state, where the NLMS data is centered on approximately 1990. It displays the well-documented geographic clustering of especially-high mortality states in th
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Vadimezan br Disclaimer br Introduction Adolescent substance
2018-11-02
Disclaimer Introduction Adolescent substance misuse is a significant problem in developed countries (Currie et al., 2012; U.S. Department of Health and Human Services, 2007) and early initiation of substance use is associated with higher levels of substance-related harm during adulthood (Dawso
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Not only the culture but also the
2018-11-01
Not only the culture, but also the domicile and gender may influence sleep. Girls have been found to have longer sleep and they spend more time in motionless sleep [16]. To make the issue further complex, a study from Brazil showed that girls had a longer nighttime sleep on holidays but not on weekd
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ppar antagonist Optical detection has been thought incapable
2018-11-01
Optical detection has been thought incapable of measuring absolute concentrations of blood components. Therefore, most researchers have employed multicomponent analysis techniques, such as partial least squares or principal component analysis. However, these analysis methods have central contradicti
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SM-164 Our results are in accordance with recent studies usi
2018-11-01
Our results are in accordance with recent studies using RT combined with mAb-mediated blockade of PD-1 or PD-L1 in mouse models of melanoma (Sharabi et al., 2015), breast carcinoma (Deng et al., 2014; Sharabi et al., 2015), colon adenocarcinoma (Deng et al., 2014), glioma (Zeng et al., 2013) and mul
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Oxysterols serve as endogenous ligands of liver
2018-11-01
Oxysterols serve as endogenous ligands of liver X receptors (LXRα (NR1H3)/LXRβ (NR1H2)) (Janowski et al., 1996). In addition to their established role in cholesterol metabolism (Janowski et al., 1999), LXRs also suppress inflammatory gene expression, thus controlling immune response and inflammation
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br Data In addition to make the figures in the
2018-11-01
Data In addition, to make the figures in the text become clearer, all of the figures were processed by Photoshop 8.1 software. ChemOffice 2008 was used for drawing the structures of pilocarpine hydrochloride red 1 and acid green 50 (Fig. 1). Experimental design, materials and methods Acknow
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The NMR analysis of the reaction media of CHO and
2018-11-01
The NMR analysis of the reaction media of β-CHO and t-BuOOH oxidation, revealed the formation of Prostaglandin E2 6. The results obtained from 1D 1H, COSY and 1D selective NOESY experiments of the aqueous media of reaction, allowed the 1H NMR characterization of the molecule. Fig. 1 shows the struc
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br Acknowledgements Many thanks to C
2018-11-01
Acknowledgements Many thanks to C. Johnson for providing unpublished data. This research was supported by an Australian Postgraduate Award and Australian Government Caring for our Country 2 Target Area Grant 2013/14 (Project ID: TAG14-00542) Bettongia tropica population status, viability and impa
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